Oxo-type organophosphate-resistant acetylcholinesterase from organophosphate-unsusceptible Culex tritaeniorhynchus.
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منابع مشابه
Acetylcholinesterase Inhibition in Organophosphate-Resistant Rhyzopertha dominica (F.) (Coleoptera: Bostrichidae)
RESUMO Populações de Rhyzopertha dominica (F.) resistente e susceptível a inseticidas fosforados foram investigadas para verificar a ocorrência de acetilcolinesterase alterada. Malaoxon, a diferentes concentrações, foi utilizado como inibidor em ensaios colorimétricos "in vitro". Populações resistentes provenientes dos municípios de Patrocínio (Minas Gerais, Brasil) e Riley (Kansas, E.U.A.) apr...
متن کاملOverproduction of detoxifying esterases in organophosphate-resistant Culex mosquitoes and their presence in other insects.
Antisera raised against the denatured polypeptide of two organophosphate-detoxifying esterases (B1 and A1) of Culex mosquitoes were used in an immunoblot method to quantify esterase production in resistant versus susceptible strains and to detect the presence of immunologically related proteins in other insects. It was demonstrated that esterase B1 of Culex quinquefasciatus and esterase A1 of C...
متن کاملAging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase.
The high reactivity of cholinesterases (ChEs) toward organophosphorus (OP) compounds has led to propose recombinant ChEs as bioscavengers of nerve agents. The bioscavenging potential of recombinant ChEs can be enhanced by conjugation of polyethylene glycol (PEG) moieties, to extend their circulatory residence. However, the ability of exogenously administered ChEs to confer long-term protection ...
متن کاملFullerene antioxidants decrease organophosphate-induced acetylcholinesterase inhibition in vitro.
Although organophosphate (OP)-induced acetylcholinesterase (AChE) inhibition is the critical mechanism causing toxicities that follow exposure, other biochemical events, including oxidative stress, have been reported to contribute to OP toxicity. Fullerenes are carbon spheres with antioxidant activity. Thus, we hypothesized that fullerenes could counteract the effects of OP compounds and tested...
متن کاملPlant-parasitic Nematode Acetylcholinesterase Inhibition by Carbamate and Organophosphate Nematicides.
The sensitivity of acetylcholinesterases (ACHE) isolated from the plant-parasitic nematodes Meloidogyne arenaria, M. incognita, and Heterodera glycines and the free-living nematode Caenorhabditis elegans to carbamate and organophosphate nematicides was examined. The AChE from plant-parasitic nematode species were more sensitive to carbamate inhibitors than was AChE from C. elegans, but response...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1988
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.36.312